This critical tri-peptide is found concentrated in the liver and is one of the most potent low molecular weight thiols. Reduced glutathione (GSH) is a is technically a tripeptide, comprised of the aminos acids L-glutamine, L-cysteine, and glycine. Not only considered a potent, protective antioxidant, it is considered as a naturally-occurring nutrient that supports the function of liver health as well as gastric and muscle energetics. It has also demonstrated capacity to impact skin health as well. The most concentrated amounts of glutathione are found in the liver.
Raising GSH level has been clinically proven to be beneficial for people afflicted with a number of ailments such as AIDS, Alzheimer’s, asthma, burns, all cancers, cataracts, chronic fatigue syndrome, diabetes, autoimmune disorders, diseases of liver, kidneys, lungs, heart, and digestive system, flu, fibromyalgia, hepatitis, multiple sclerosis, Parkinson’s, physical trauma, skin disorders, seizures, tumors, and more.
Glutathione plays crucial roles in the detoxification and antioxidant systems of cells and has been used to treat acute poisoning and chronic liver diseases by intravenous injection. Peer-reviewed, published clinical research has demonstrated that glutathione is lowered in subjects with cirrhosis or chronic alcoholic intake. In fact, it is a foundational nutrient in the detoxification of liver, lungs, gut epithelium, lungs, and ocular tissues.
Scientists have also studied the therapeutic effects of oral administration of glutathione in patients with nonalcoholic fatty liver disease (NAFLD). NAFLD is an important pathology behind chronic liver injury worldwide. The open-label, single arm, multi-center clinical trial involved 29 patients taking 300 mg glutathione per day for a 4 month period. One of the primary biomarkers reviewed in the study is ALT (Alanine Aminotransferase), an enzyme that is leaked from the liver cells, and its presence is found higher than normal amounts when the liver is in distress. After 4 months of supplementation with 300 mg glutathione, the ALT levels dropped significantly. While liver biopsy was not part of this clinical protocol, it can be inferred that the ALT liver enzyme decline is indicative of liver protection. View research
Certain chemicals found in foods and spices are known to contribute to glutathione production in the body, assist in recycling oxidized glutathione back Setu Glutathione is made by biological fermentation and is bioidentical to that made in the body. Furthermore, it is in the reduced, non-oxidized form and made to USP/EP purity standards.