Vitamin D3, also known as cholecalciferol, is one of two forms of vitamin D, the “sunshine vitamin.” (The other form of vitamin D is called ergosterol and is also known as Vitamin D2.) Vitamin D3 is made naturally by the body when the skin’s 7-dehydrocholesterol is exposed to sunlight (or UVB rays, to be precise). It is the more potent of the two forms and is preferred by the body for various activities. Vitamin D3 is vital for the body to absorb calcium and for healthy bones. Vitamin D3 is also important for the health of the cardiovascular, neuromuscular and immune systems. Studies have shown that vitamin D3 deficiency can also increase the risks of cancers (breast, colon, prostate), weight gain, heart disease and depression, among others.
Vitamin D3 participates in a large number of metabolic processes. Chief among them is the absorption and proper utilization of calcium. Its deficiency results in poor calcium absorption, leading to rickets (soft bones) in children and osteomalacia (fragile misshapen bones) in adults. Apart from these, vitamin D deficiency can also result in skeletal diseases, metabolic disorders, cardiovascular diseases, cancers, autoimmune diseases, cognitive problems and infections. Some foods like fish liver oil, eggs and meats contain vitamin D3. However, in general, D3 is found in very limited quantities in food and therefore the diet is often inadequate to prevent D 3 deficiency for our body ;exposure to sunlight remains the best source of this vital nutrient.
In a randomized, double blind (the “gold standard”), placebo-controlled trial on 93 patients with congestive heart failure, researchers tried to assess the effectiveness of vitamin D3 supplementation on the progression of the disease. After using a dosage of 2000 IU vitamin D3 per day in one group (the other was given placebo) for nine months, researchers performed biochemical testing of blood samples from both groups. In the group that was given vitamin D3 supplementation, scientists found an increase in the concentration of an anti-inflammatory compound of the immune system, cytokine IL-10. Concentrations of the pro-inflammatory cytokine, TNF-α, on the other hand, was found to be reduced. Cytokine IL-10 is important for cardiovascular health and research has also indicated that reduced levels of serum IL-10 can lead to severe atherosclerosis (blocking of blood vessels supplying blood to the heart muscles), leading to heart failure. This research underlines the importance of vitamin D3 in protection against cardiovascular diseases. View research
At Setu, we manufacture D3 from lanolin from sheep. Lanolin is a waxy substance found on the skin of the sheep. Vitamin D3 thus produced is bioidentical to the one found in the human body and has equal potency.
Vitamin D3 supplementation is necessary because we do not get enough of this vitamin from our diet. Moreover, vegetarians are at a disadvantage because their diet does not provide them with the types of foods that contain significant amounts of vitamin D3. Even non-vegetarian diet is insufficient in providing sufficient quantities of vitamin D3. Not everybody gets enough exposure to sunlight. Different skin tones make it difficult to get enough UVB rays. Also use of chemical sunscreens does not allow proper penetration of these rays. Thus it is necessary to rely on a high quality vitamin D3 supplement for a healthy metabolism.
Pressure Pal and Beat It are two of Setu’s products that contain vitamin D3. Pressure Pal contains CoQ10, Grape Seed extract and Bilberry anthocyanins along with vitamin D3 and helps maintain healthy blood pressure. Beat It is a potent combination of vitamins and minerals for heart health. It contains CoQ10, vitamin B12, Folic Acid, along with vitamin D3.